产品货号：
Z17063
中文名称：
GFRA1抗体
英文名称：
Anti-GFRA1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-GFRA1 Antibody |
| 指标别名 | Golgi-associated;gamma adaptin ear-containing;ARF-binding protein 1;Gga1;;GFRA1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | GFRA1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | GFR alpha 1 antibody was raised against a 14 amino acid peptide near the center of human GFR alpha 1.The immunogen is located within amino acids 360 - 410 of GFR alpha 1. |
| 计算分子量 | 51kDa |
| 成分 | GFR alpha 1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | GFR alpha 1 Antibody is Antibody is DEAE purified. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | GFR alpha 1 antibody can be stored at 4℃ up to one year.Antibodies should not be exposed to prolonged high temperatures. |
| 背景资料 | Glial cell line-derived neurotrophic factor (GDNF) is a potent survival factor for central and peripheral neurons and is essential for the development of kidneys and the enteric nerves system.Physiological responses to GDNF require the presence of a novel glycosylphosphadidylinositol linked protein GDNFRalpha,which is a cell surface receptor for GDNF.The cDNAs encoding GDNFRalpha from human,rat,chicken and mouse have been cloned recently.GDNFRalpha was also termed Ret ligand 1 (RETL1) or TGF-beta-related neurotrophic factor receptor 1 (TrnR1) and nominated as GFR汐-1 recently.GFR汐-1 binds GDNF specifically and mediates activation of the Ret protein tyrosine kinase (PTK).Thus,GDNF,GFR汐and the Ret PTK form a complex to transduce GDNF signal and to mediate GDNF function. |
| Uniprot ID | P56159 |
| 基因名全称 | GDNF family receptor alpha 1 |
| 蛋白名全称 | GDNF family receptor alpha 1 |
| 推荐稀释比 | GFR alpha 1 antibody can be used for detection of GFR alpha 1 by Western blot at 1μg/mL.Antibody can also be used for immunohistochemistry starting at 1μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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